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Immuno suppressant for treatment of Atopic Dermatitisin Dogs.
Work on the specific cells in immune system which cause allergic reaction.
Wide distribution in tissues, concentrates on skin and relieves redness and lesions of skin.
Available in 3-mode different strengths for dosing convenience as per body weight.
Useful for other immune medicated skin diseases like Perianal fistulas.
Compositions:Each soft gelatin capsule contains:
Cyclosporine USP - 100 mg: in the color of Ferric Oxide Red,
Cyclosporine USP - 50 mg: in the color of Ferric Oxide Red and Ferric Oxide Black,
Cyclosporine USP - 25 mg: in the color of Ferric Oxide Red.
Category: Potent Immuno suppressive Agent.
Pharma codynamics: The Cyclosporine is a potentimmunue - suppressive agent which has shown to work via suppression of T-helperand T-suppressor cells. Inhibition of interleukin-2. Doesn't impair the hematopoietic system/cell-mediated immunologic responses. The decrease in CD4& CD8 cells was not shown in dogs receiving 20 mg/kg/day of cyclosporine for 56 days. The medicine is not corticosteroid or an antihistamine.
Pharma cokinetics:This is extensively metabolized by the cytochrome P-450 enzyme system in the liver with a lesser degree of gastrointestinal tract and the kidney
Treatment for the atopic dermatitis in dogs.
Used as an aid in the treatment of perianal fistulaein dogs. The fistula (also known as perianal fistula) is a syndrome of swollen,ulcer & draining sinuses around the anus (perianal), region of dogs, mostlyin German Shepherds, which is thought to be an immune-mediated condition.
The Perianal fistula is extremely painful,unpleasant smell and often requires surgery. The limited study has shown on theuse of cyclosporine for the treatment of perianal fistulae in dogs. It may helpto reduce or resolve symptoms.