Africa, Middle East, Western Europe, Eastern Europe, South America, North America, Central America, Australia, Asia
Vaccine for dogs against Rabies and canineleptospiros is caused by L. interrogans serotype canicola and icterohaemorrhagiae.
Systemic reactions include fever, depression, loss of appetite, lethargy and weakness. They usually appear within 1-2 days of vaccination and then disappear. Nervous system problems have been seen after vaccination with modified live rabies (no longer available) and caninedis temper vaccines.